Version

Mayhem

ColorlessPowerRare
At the start of your turn, play the top card of your Draw Pile.

After your Energy resets and your Hand is drawn each turn, the top card of your Draw Pile is played for free with a random target; two copies play two cards. A Curse, Status or other Unplayable card on top is simply moved to the Discard Pile instead. Upgrading only lowers the cost from 2 to 1.

Pool
Colorless
Type
Power
Rarity
Rare
Cost
21 Energy
Target
Yourself

When to take Mayhem

Take it in a deck where almost every card is good to fire blind, like Attacks, Block or cheap Skills. Skip it with expensive setup cards or debuffs you want to aim yourself.

Cards that synergize with Mayhem

Catastrophe
Skill
2
Play 2 random cards from your Draw Pile.
Catastrophe and Havoc are the same idea on demand.Play 2 random cards from your Draw Pile.
Havoc
Skill
1
Play the top card of your Draw Pile and Exhaust it.
Catastrophe and Havoc are the same idea on demand.Play the top card of your Draw Pile and Exhaust it.
Stratagem
Power
1
Whenever you shuffle your Draw Pile, choose a card from it to put into your Hand.
Stratagem lets you pick what goes on top after a shuffle.Whenever you shuffle your Draw Pile, choose a card from it to put into your Hand.
Nostalgia
Power
1
The first Attack or Skill you play each turn is placed on top of your Draw Pile.
Nostalgia puts your first played card back on top for Mayhem to replay.The first Attack or Skill you play each turn is placed on top of your Draw Pile.
Headbutt
Attack
1
Deal 9 damage.
Put a card from your Discard Pile on top of your Draw Pile.
Headbutt and Cosmic Indifference choose the top card by hand.Deal 9 damage.
Put a card from your Discard Pile on top of your Draw Pile.
Cosmic Indifference
Skill
1
Gain 6 Block.
Put a card from your Discard Pile on top of your Draw Pile.
Headbutt and Cosmic Indifference choose the top card by hand.Gain 6 Block.
Put a card from your Discard Pile on top of your Draw Pile.
Signal Boost
Skill
1
The next Power you play is played an additional time.
Exhaust.
Signal Boost triggers on Powers played, and Mayhem is oneThe next Power you play is played an additional time.
Exhaust.
Storm
Power
1
Whenever you play a Power, Channel 1 Lightning.
Storm triggers on Powers played, and Mayhem is oneWhenever you play a Power, Channel 1 Lightning.
Subroutine
Power
1
Whenever you play a Power, gain .
Subroutine triggers on Powers played, and Mayhem is oneWhenever you play a Power, gain .
Synthesis
Attack
2
Deal 14 damage.
The next Power you play costs 0 .
Synthesis triggers on Powers played, and Mayhem is oneDeal 14 damage.
The next Power you play costs 0 .
Right Hand Hand
Attack
0
Osty deals 4 damage.
Whenever you play a card that costs or more, return this to your Hand from the Discard Pile.
Right Hand Hand triggers on cards that cost 2 or more, and Mayhem is oneOsty deals 4 damage.
Whenever you play a card that costs or more, return this to your Hand from the Discard Pile.
Danse Macabre
Power
1
Whenever you play a card that costs or more, gain 4 Block.
Danse Macabre triggers on cards that cost 2 or more, and Mayhem is oneWhenever you play a card that costs or more, gain 4 Block.

Relics that synergize with Mayhem

Permafrost
Permafrost triggers on Powers played, and Mayhem is oneThe first time you play a Power each combat, gain 7 Block.
Lost Wisp
Lost Wisp triggers on Powers played, and Mayhem is oneWhenever you play a Power, deal 8 damage to ALL enemies.
Mummified Hand
Mummified Hand triggers on Powers played, and Mayhem is oneWhenever you play a Power, a random card in your Hand is free to play that turn.
Game Piece
Game Piece triggers on Powers played, and Mayhem is oneWhenever you play a Power, draw 1 card.
Intimidating Helmet
Intimidating Helmet triggers on cards that cost 2 or more, and Mayhem is oneWhenever you play a card that costs or more, gain 4 Block.
✦
Beacon of Hope
Power
1
Whenever you gain Block on your turn, other players gain half that much Block.
Calamity
Power
3
Whenever you play an Attack, add a random Attack into your Hand.
Entropy
Power
1
At the start of your turn, Transform 1 card in your Hand.
Eternal Armor
Power
3
Gain 9 Plating.
Nostalgia
Power
1
The first Attack or Skill you play each turn is placed on top of your Draw Pile.
Rolling Boulder
Power
3
At the start of your turn, deal 5 damage to ALL enemies and increase this damage by 5.
Automation
Power
1
Every 10 cards you draw, gain .
Fasten
Power
1
Gain an additional 4 Block from Defend cards.

Changes by version

  1. 5 Feb 2026Bug fixArt of WarInternal playtest
    Art of War relic now properly disables Energy gain for the turn when an effect like Mayhem auto-plays an attack on turn start
  2. 11 Dec 2025Bug fixBombardmentHowl from BeyondExhaustInternal playtest
    When Mayhem card auto-plays Bombardment (or Howl From Beyond with added Exhaust), the card is no longer played a second time via its "plays from the Exhaust pile" effect
  3. 30 Oct 2025Bug fixRetainConvergenceInternal playtest
    Cards that Retain your hand this turn (Convergence, etc.) now work properly when auto-played by Mayhem card
All 10 patch notes7 older
  1. 27 Aug 2025TextInternal playtest
    Updated wording
    Bug fixUnceasing TopInternal playtest
    Unceasing Top relic is no longer triggered by card plays from effects that occur before the player draws their hand (ex. Mayhem card)
  2. 10 Jul 2025Bug fixRelaxInternal playtest
    Fixed an interaction between Mayhem and Relax
  3. 20 Jun 2025Bug fixHello WorldInternal playtest
    Fixed an issue where, if Mayhem card autoplayed Hello World card, Hello World's effect would trigger immediately after
  4. 27 Feb 2025Bug fixInternal playtest
    When cards that require card selection are autoplayed by Mayhem, the start of turn sequence no longer continues behind the choice screen
  5. 6 Feb 2025RarityUncommonRareInternal playtest
    Rarity changed from Uncommon to Rare and now triggers before card draw
  6. 7 Nov 2024Bug fixInternal playtest
    Mayhem-ing a card afflicted with Forced Insight no longer softlocks the game
  7. 1 Sep 2023ArtInternal playtest
    Updated Mayhem card art

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam