Entropy

ColorlessPowerRare
At the start of your turn, Transform 1 card in your Hand.

At the start of each of your turns, after the draw, a selection prompt lets you choose 1 card in hand; it is transformed into a random card of any rarity for this combat only, and your deck outside the fight is untouched. You pick the victim, so feed it a Strike, a Status or a Curse. Upgrading adds Innate so it is in your opening hand.

Pool
Colorless
Type
Power
Rarity
Rare
Cost
1 Energy
Target
Yourself
Unlock
PreonFill the score bar at the end of a run

When to take Entropy

Good in a deck still stuffed with Strikes and Defends, ideally in Act 1 so many fights benefit from the free swap. Feed it your Statuses and Curses first.

Cards that synergize with Entropy

Overclock
Skill
0
Draw 2 cards.
Add a Burn into your Discard Pile.
For the Defect, Overclock and TURBO hand it a Burn or a Void to eat each turn.Draw 2 cards.
Add a Burn into your Discard Pile.
TURBO
Skill
0
Gain .
Add a Void into your Discard Pile.
For the Defect, Overclock and TURBO hand it a Burn or a Void to eat each turn.Gain .
Add a Void into your Discard Pile.
Jack of All Trades
Skill
0
Add 1 random Colorless card into your Hand.
Exhaust.
Jack of All Trades adds cheap fodder you can reroll.Add 1 random Colorless card into your Hand.
Exhaust.
Signal Boost
Skill
1
The next Power you play is played an additional time.
Exhaust.
Signal Boost triggers on Powers played, and Entropy is oneThe next Power you play is played an additional time.
Exhaust.
Storm
Power
1
Whenever you play a Power, Channel 1 Lightning.
Storm triggers on Powers played, and Entropy is oneWhenever you play a Power, Channel 1 Lightning.
Subroutine
Power
1
Whenever you play a Power, gain .
Subroutine triggers on Powers played, and Entropy is oneWhenever you play a Power, gain .
Synthesis
Attack
2
Deal 14 damage.
The next Power you play costs 0 .
Synthesis triggers on Powers played, and Entropy is oneDeal 14 damage.
The next Power you play costs 0 .

Relics that synergize with Entropy

Frozen Egg
Frozen Egg upgrades it on pickup.Whenever you add a Power into your Deck, Upgrade it.
Game Piece
Game Piece draws when you play it and Permafrost blocks for 7.Whenever you play a Power, draw 1 card.
Permafrost
Game Piece draws when you play it and Permafrost blocks for 7.The first time you play a Power each combat, gain 7 Block.
Lost Wisp
Lost Wisp triggers on Powers played, and Entropy is oneWhenever you play a Power, deal 8 damage to ALL enemies.
Mummified Hand
Mummified Hand triggers on Powers played, and Entropy is oneWhenever you play a Power, a random card in your Hand is free to play that turn.
✦
Beacon of Hope
Power
1
Whenever you gain Block on your turn, other players gain half that much Block.
Mind Blast
Attack
1
Innate.
Deal damage equal to the number of cards in your Draw Pile.
Dramatic Entrance
Attack
0
Innate.
Deal 11 damage to ALL enemies.
Exhaust.
Afterimage
Power
1
Whenever you play a card, gain 1 Block.
Aggression
Power
1
At the start of your turn, put a random Attack from your Discard Pile into your Hand and Upgrade it.
Arsenal
Power
1
Whenever you create a card, gain 1 Strength.
Call of the Void
Power
1
At the start of your turn, add 1 random card into your Hand. It gains Ethereal.
Machine Learning
Power
1
At the start of your turn, draw 1 additional card.

Changes by version

  1. 2 Jul 2026Bug fixAscender's BanePlaytest
    Fixed Entropy card being able to transform curses into Ascender's Bane
  2. 5 Feb 2026Bug fixDisintegrationMind RotSlothWaste AwayInternal playtest
    Entropy card can no longer transform status cards into Disintegration, Mind Rot, Sloth, or Waste Away cards
  3. 11 Sep 2025Upgrade+1 cardadds InnateInternal playtest
    Upgrade changed from +1 card to adding Innate
All 10 patch notes7 older
  1. 17 Jul 2025Bug fixFeedInternal playtest
    Entropy card can no longer transform cards into cards like Feed that buff the player for the whole climb
  2. 10 Jul 2025ArtInternal playtest
    Added card art
  3. 6 Feb 2025AddedInternal playtest
    Added to the game
  4. 29 Jun 2024Bug fixTezcataraInternal playtest
    Decree of Entropy card can now transform Tezcatara's Ember cards
  5. 14 Jun 2024InterfaceInternal playtest
    Cards that cannot be generated correctly are blocked from Decree of Entropy and Chrysalis
    Bug fixInternal playtest
    Decree of Entropy should replace transformed cards in the right order
  6. 7 Jun 2024CostTyrannyInternal playtest
    Changed Decree of Entropy card: is now a zero-cost token generated by Tyranny
    Bug fixInternal playtest
    Fixed softlock on Decree of Entropy card transforming curses
  7. 31 May 2024ReworkInternal playtest
    Reworked Decree of Entropy card: now transforms all cards in hand and, if upgraded, upgrades them as well

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam