Version

Cosmic Indifference

RegentSkillCommon
Gain 6 Block.
Put a card from your Discard Pile on top of your Draw Pile.

You gain 6 Block (9 upgraded), then a selection screen shows your Discard Pile and you choose one card to place on top of your Draw Pile. It becomes your next draw unless something else is put on top later. With an empty Discard Pile the card is just Block.

Character
Regent
Type
Skill
Rarity
Common
Cost
1 Energy
Target
Yourself

When to take Cosmic Indifference

A Defend replacement with a tutor attached. Take it in Act 1 over a Defend when your deck has draw-triggered or best-in-class cards worth seeing again, like Kingly Kick or Kingly Punch.

Cards that synergize with Cosmic Indifference

Kingly Kick
Attack
4
Deal 27 damage.
Whenever you draw this card, reduce its cost by 1.
Kingly Kick and Kingly Punch get better every time they are drawn, and this redraws them.Deal 27 damage.
Whenever you draw this card, reduce its cost by 1.
Kingly Punch
Attack
1
Deal 8 damage.
Whenever you draw this card, increase its damage by 4 this combat.
Kingly Kick and Kingly Punch get better every time they are drawn, and this redraws them.Deal 8 damage.
Whenever you draw this card, increase its damage by 4 this combat.
I Am Invincible
Skill
1
Gain 10 Block.
At the end of your turn, if this is on top of your Draw Pile, play it.
I Am Invincible plays itself at end of turn if it is on top of your Draw Pile, which this arranges for 10 free Block.Gain 10 Block.
At the end of your turn, if this is on top of your Draw Pile, play it.
Comet
Attack
0
5
Deal 33 damage.
Apply 3 Weak.
Apply 3 Vulnerable.
Comet comes back for a second cast.Deal 33 damage.
Apply 3 Weak.
Apply 3 Vulnerable.
Prophesize
Skill
2
Draw 6 cards.
Prophesize then draws the stacked card with five others.Draw 6 cards.
Beacon of Hope
Power
1
Whenever you gain Block on your turn, other players gain half that much Block.
Beacon of Hope makes Block count for more, and Cosmic Indifference gains itWhenever you gain Block on your turn, other players gain half that much Block.
Entrench
Skill
2
Double your Block.
Entrench makes Block count for more, and Cosmic Indifference gains itDouble your Block.
Prolong
Skill
0
Next turn, gain Block equal to your current Block.
Exhaust.
Prolong makes Block count for more, and Cosmic Indifference gains itNext turn, gain Block equal to your current Block.
Exhaust.

Relics that synergize with Cosmic Indifference

Parrying Shield
Parrying Shield makes Block count for more, and Cosmic Indifference gains itIf you end a turn with at least 10 Block, deal 6 damage to a random enemy.
Sturdy Clamp
Sturdy Clamp makes Block count for more, and Cosmic Indifference gains itUp to 10 Block persists across turns.
Pael's Legion
Pael's Legion makes Block count for more, and Cosmic Indifference gains itDoubles Block gained from a card, then goes to sleep for 2 turns.
Vambrace
Vambrace makes Block count for more, and Cosmic Indifference gains itThe first time you gain Block from a card each combat, double the amount gained.
✦
BEGONE!
Skill
1
Choose a card in your Hand to Transform into Minion Strike.
Gather Light
Skill
1
Gain 8 Block.
Gain .
Glow
Skill
1
Gain .
Draw 1 card.
Next turn, draw 1 card.
Hidden Cache
Skill
1
Gain .
Next turn, gain .
Patter
Skill
1
Gain 8 Block.
Gain 2 Vigor.
Refine Blade
Skill
1
Forge 9.
Next turn, gain .
Spoils of Battle
Skill
1
Forge 5.
Draw 2 cards.
Bundle of Joy
Skill
1
Add 3 random Colorless cards into your Hand.
Exhaust.

Changes by version

  1. 3 Jul 2025Block5(8)6(9)Internal playtest
    Block increased from 5 to 6 (upgraded 8 to 9)
  2. 30 Jan 2025Block6(9)5(8)Internal playtest
    Block decreased from 6 to 5 (upgraded 9 to 8)
  3. 16 Jan 2025Block9(12)6(9)Internal playtest
    Block gain decreased from 9 to 6 (upgraded 12 to 9)
All 4 patch notes1 older
  1. 9 Jan 2025ReworkInternal playtest
    Reworked the card
    Block20(24)13(17)ExhaustExhaustno ExhaustInternal playtest
    Block gain decreased from 20 to 13 (upgraded 24 to 17) and removed Exhaust

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam