Alchemize

ColorlessSkillRare
Procure a random potion.
Exhaust.

Playing it adds a random potion to your first empty potion slot, then the card exhausts. Upgrading drops the cost from 1 to 0. If every slot is full the procure fails and nothing arrives, so drink or discard first. The card is excluded from random in-combat generation, so Discovery and similar effects never offer it.

Pool
Colorless
Type
Skill
Rarity
Rare
Cost
10 Energy
Target
Yourself
Unlock
SlumberFill the score bar at the end of a run

When to take Alchemize

Worth a shop visit once you have free potion slots to fill, especially with Potion Belt or a plan to use potions in elite fights. Buy it early, when each extra potion matters most.

Cards that synergize with Alchemize

Evil Eye
Skill
1
Gain 8 Block.
Gain another 8 Block if you have Exhausted a card this turn.
Evil Eye triggers when cards are Exhausted, and Alchemize Exhausts itselfGain 8 Block.
Gain another 8 Block if you have Exhausted a card this turn.
Pact's End
Attack
0
If you have 3 or more cards in your Exhaust Pile,
deal 17 damage to ALL enemies.
Pact's End triggers when cards are Exhausted, and Alchemize Exhausts itselfIf you have 3 or more cards in your Exhaust Pile,
deal 17 damage to ALL enemies.
Ashen Strike
Attack
1
Deal 6 damage.
Deals 3 additional damage for each card in your Exhaust Pile.
Ashen Strike triggers when cards are Exhausted, and Alchemize Exhausts itselfDeal 6 damage.
Deals 3 additional damage for each card in your Exhaust Pile.
Feel No Pain
Power
1
Whenever a card is Exhausted, gain 3 Block.
Feel No Pain triggers when cards are Exhausted, and Alchemize Exhausts itselfWhenever a card is Exhausted, gain 3 Block.
Forgotten Ritual
Skill
1
If you Exhausted a card this turn, gain .
Exhaust.
Forgotten Ritual triggers when cards are Exhausted, and Alchemize Exhausts itselfIf you Exhausted a card this turn, gain .
Exhaust.
Dark Embrace
Power
2
Whenever a card is Exhausted,
draw 1 card.
Dark Embrace triggers when cards are Exhausted, and Alchemize Exhausts itselfWhenever a card is Exhausted,
draw 1 card.
Midnight
Attack
12
Deal 60 damage.
Costs 1 less for each card Exhausted this combat by ANYONE.
Midnight triggers when cards are Exhausted, and Alchemize Exhausts itselfDeal 60 damage.
Costs 1 less for each card Exhausted this combat by ANYONE.

Relics that synergize with Alchemize

Potion Belt
Potion Belt doubles the room it can fill.Upon pickup, gain 2 potion slots.
Reptile Trinket
Reptile Trinket pays 3 Strength every time you drink what it made.Whenever you use a potion, gain 3 Strength this turn.
White Beast Statue
White Beast Statue keeps the belt topped up between fights.Potions always appear in combat rewards.
Tiny Mailbox
Tiny Mailbox and Delicate Frond share the same plan of more potions than you can use.Whenever you Rest, procure 2 random potions.
Delicate Frond
Tiny Mailbox and Delicate Frond share the same plan of more potions than you can use.At the start of each combat, fill all empty potion slots with random potions.
Burning Sticks
Burning Sticks triggers when cards are Exhausted, and Alchemize Exhausts itselfThe first time each combat you Exhaust a Skill, add a copy of it into your Hand.
Charon's Ashes
Charon's Ashes triggers when cards are Exhausted, and Alchemize Exhausts itselfWhenever you Exhaust a card, deal 3 damage to ALL enemies.
Joss Paper
Joss Paper triggers when cards are Exhausted, and Alchemize Exhausts itselfEvery 5 times you Exhaust a card, draw 1 card.
Forgotten Soul
Forgotten Soul triggers when cards are Exhausted, and Alchemize Exhausts itselfWhenever you Exhaust a card, deal 1 damage to a random enemy.

Rules and timing

Excluded from random card generation in combat.

✦
Anointed
Skill
1
Put every Rare card from your Draw Pile into your Hand.
Exhaust.
Mimic
Skill
1
Gain Block equal to the Block on another player.
Exhaust.
Scrawl
Skill
1
Draw cards until your Hand is full.
Exhaust.
Discovery
Skill
1
Choose 1 of 3 random cards to add into your Hand. It's free to play this turn.
Exhaust.
Huddle Up
Skill
1
ALL players draw 2 cards.
Exhaust.
Master of Strategy
Skill
0
Draw 3 cards.
Exhaust.
Secret Technique
Skill
0
Put a Skill from your Draw Pile into your Hand.
Exhaust.
Secret Weapon
Skill
0
Put an Attack from your Draw Pile into your Hand.
Exhaust.

Changes by version

  1. 25 Apr 2025PoolThe SilentInternal playtest
    Pool changed from Silent to Colorless
  2. 9 Jan 2025NerfFruit JuiceRegen PotionFairy in a BottleInternal playtest
    Can no longer procure Fruit Juice, Regen Potion, or Fairy in a Bottle potions
    TextInternal playtest
    Alchemize card now uses the word "Procure" instead of "Obtain"

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam