Version

Bubble Bubble

SilentSkillUncommon
If the enemy has Poison, apply 9 Poison.

Checks whether the target has any Poison. If it does, apply 9 more (12 upgraded); if not, nothing happens and the Energy is still spent. The card glows gold when at least one enemy is poisoned. It applies Poison once, so per-application effects fire once.

Character
Silent
Type
Skill
Rarity
Uncommon
Cost
1 Energy
Target
One enemy
Unlock
Bigger PreyBeat Act 1 with the Silent

When to take Bubble Bubble

Worth it once your deck can Poison reliably every fight, not before. With a Poison opener it is the cheapest 9 Poison in the pool, so upgrade it once Poison is your main damage.

Cards that synergize with Bubble Bubble

Noxious Fumes
Power
1
At the start of your turn, apply 2 Poison to ALL enemies.
Noxious Fumes does the same each turn.At the start of your turn, apply 2 Poison to ALL enemies.
Poisoned Stab
Attack
1
Deal 6 damage.
Apply 3 Poison.
Poisoned Stab and Deadly Poison are cheap enablers.Deal 6 damage.
Apply 3 Poison.
Deadly Poison
Skill
1
Apply 5 Poison.
Poisoned Stab and Deadly Poison are cheap enablers.Apply 5 Poison.
Accelerant
Power
1
Poison is triggered 1 additional time.
Accelerant ticks it twice per turn.Poison is triggered 1 additional time.
Burst
Skill
1
This turn, your next Skill is played an extra time.
Burst plays it twice for 18.This turn, your next Skill is played an extra time.
Snakebite
Skill
2
Retain.
Apply 7 Poison.
Snakebite applies Poison, which Bubble Bubble builds onRetain.
Apply 7 Poison.
Corrosive Wave
Skill
1
Whenever you draw a card this turn, apply 2 Poison to ALL enemies.
Corrosive Wave applies Poison, which Bubble Bubble builds onWhenever you draw a card this turn, apply 2 Poison to ALL enemies.
Haze
Skill
3
Sly.
Apply 4 Poison to ALL enemies.
Haze applies Poison, which Bubble Bubble builds onSly.
Apply 4 Poison to ALL enemies.
Bouncing Flask
Skill
2
Apply 3 Poison to a random enemy 3 times.
Bouncing Flask applies Poison, which Bubble Bubble builds onApply 3 Poison to a random enemy 3 times.
Envenom
Power
2
Whenever an Attack deals unblocked damage, apply 1 Poison.
Envenom applies Poison, which Bubble Bubble builds onWhenever an Attack deals unblocked damage, apply 1 Poison.

Relics that synergize with Bubble Bubble

Twisted Funnel
Twisted Funnel poisons everyone at combat start, so it is always live.At the start of each combat, apply 4 Poison to ALL enemies.
Snecko Skull
Snecko Skull makes it 10.Whenever you apply Poison, apply an additional 1 Poison.
✦
Mirage
Skill
1
Gain Block equal to Poison on ALL enemies.
Exhaust.
Outbreak
Power
1
Every 3 times you apply Poison, deal 11 damage to ALL enemies.
Accelerant
Power
1
Poison is triggered 1 additional time.
Bouncing Flask
Skill
2
Apply 3 Poison to a random enemy 3 times.
Corrosive Wave
Skill
1
Whenever you draw a card this turn, apply 2 Poison to ALL enemies.
Deadly Poison
Skill
1
Apply 5 Poison.
Haze
Skill
3
Sly.
Apply 4 Poison to ALL enemies.
Concoct
Skill
0
Choose another player. Whenever their Attacks deal unblocked damage this turn, they apply 3 Poison.

Changes by version

  1. 15 Jan 2026ChangeCorrosive WaveInternal playtest
    Changed Trophies Epoch unlocks: replaced Corrosive Wave card to Bubble Bubble
  2. 8 Jan 2026Poison upgrade+2+3Internal playtest
    Upgrade Poison increased from +2 to +3
  3. 1 Jan 2026ReworkInternal playtest
    Reworked the card
All 8 patch notes5 older
  1. 9 Oct 2025ArtInternal playtest
    Added portrait art
  2. 18 Sep 2025Poison5(7)3(4)RarityRareUncommonInternal playtest
    Poison decreased from 5 to 3 (upgraded 7 to 4) and rarity changed from Rare to Uncommon
  3. 3 Jul 2025ArtInternal playtest
    Added beta portrait art
  4. 12 Jun 2025ReworkInternal playtest
    Reworked the card
  5. 5 Jun 2025AddedInternal playtest
    Added to the game

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam