
Lizard Tail
Rare
When your HP would be reduced to 0, heal to 50% of your Max HP instead (works once).
When damage or HP loss would kill you, the relic steps in once per run: instead of dying you are healed by half your Max HP, never less than 1. Afterward it is used up and shown disabled for the rest of the run.
Rarity
Rare
Character
All characters
Shop price
275 gold
When to take Lizard Tail
Take it over minor stat relics whenever your HP is unstable: insurance for pushing elites and bosses you are not sure of. A higher Max HP makes the revive bigger.
Cards that synergize with Lizard Tail

Offering
Skill
0
Lose 6 HP.
Gain .
Draw 3 cards.
Exhaust.
Gain .
Draw 3 cards.
Exhaust.
OfferingSelf-damage cards like Offering and Hemokinesis get safer.Lose 6 HP.
Gain .
Draw 3 cards.
Exhaust.
Gain .
Draw 3 cards.
Exhaust.

Hemokinesis
Attack
1
Lose 2 HP.
Deal 15 damage.
Deal 15 damage.
HemokinesisSelf-damage cards like Offering and Hemokinesis get safer.Lose 2 HP.
Deal 15 damage.
Deal 15 damage.
Relics that synergize with Lizard Tail
MangoMangoMango, Looming Fruit and Lee's Waffle raise the 50% you come back with.Upon pickup, raise your Max HP by 14.
Looming FruitLooming FruitMango, Looming Fruit and Lee's Waffle raise the 50% you come back with.Upon pickup, raise your Max HP by 31.
Lee's WaffleLee's WaffleMango, Looming Fruit and Lee's Waffle raise the 50% you come back with.Upon pickup, raise your Max HP by 7 and heal all of your HP.
Red SkullRed SkullRed Skull turns on at exactly that HP.While your HP is at or below 50%, you have 3 additional Strength.
Meat on the BoneMeat on the BoneMeat on the Bone heals 12 more after the fight.If your HP is at or below 50% at the end of combat, heal 12 HP.
Changes by version
- The descriptions for Fairy in a Bottle potion and Lizard Tail relic now specify that they trigger specifically when you reach 0 HP, rather than when you die in any manner
- 12 Mar 2026Bug fixFairy in a BottleFixed Fairy in a Bottle and Lizard Tail relics not healing you when your Max HP is 1
- You can no longer use Lizard Tail relic to survive The Insatiable eating you
All 7 patch notes4 older
- Sandpit death goes through Fairy in a Bottle and Lizard Tail relics
- Abandon Run is no longer blocked by Fairy in a Bottle/Lizard Tail
- Fixed softlock from Lizard Tail relic
- Added Lizard Tail relic
Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

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