
Pandora's Box
Ancient
On pickup, every basic Strike and Defend in your deck that can be removed is transformed at once, each into its own random card of any rarity, and a screen shows the results. Cards that cannot be removed are skipped, which includes Strikes made Eternal by Nutritious Soup. It fires once, so it cannot be traded in multiplayer.
Rarity
Ancient
Character
All characters
When to take Pandora's Box
Take it almost always in Act 1: it swaps eight or nine basics for real cards, an enormous jump in power. Later, once basics are gone, it does less and can even hurt a Strike deck.
Relics that synergize with Pandora's Box
Dolly's MirrorDolly's MirrorKeep the hits with Dolly's Mirror and Pael's Growth, and clean up the misses with Empty Cage or Precise Scissors.Upon pickup, obtain an additional copy of a card in your Deck.
Pael's GrowthPael's GrowthKeep the hits with Dolly's Mirror and Pael's Growth, and clean up the misses with Empty Cage or Precise Scissors.Upon pickup, Enchant a card with Clone.
Empty CageEmpty CageKeep the hits with Dolly's Mirror and Pael's Growth, and clean up the misses with Empty Cage or Precise Scissors.Upon pickup, remove 2 cards from your Deck.
Precise ScissorsPrecise ScissorsKeep the hits with Dolly's Mirror and Pael's Growth, and clean up the misses with Empty Cage or Precise Scissors.Upon pickup, remove 1 card from your Deck.
New LeafNew LeafNew Leaf and Astrolabe are more of the same idea, and Bellows upgrades whatever the new hand is on turn 1.Upon pickup, Transform 1 card.
AstrolabeAstrolabeNew Leaf and Astrolabe are more of the same idea, and Bellows upgrades whatever the new hand is on turn 1.Upon pickup, Transform 3 cards, then Upgrade them.
BellowsBellowsNew Leaf and Astrolabe are more of the same idea, and Bellows upgrades whatever the new hand is on turn 1.The first Hand you draw each combat is Upgraded.
Changes by version
- 28 May 2026Bug fixFixed the card inspection button blocking the "accept" hotkey on the Pandora's Box card view screen
- Fixed card inspection button blocking "accept" hotkey when looking at the Pandora's Box relic card view screen
All 8 patch notes5 older
- Pandora's Box relic now has an Accept button
- Updated wording for Pandora's Box relic's info text in the card view screen
- Pandora's Box relic now flashes Egg relics over upgraded cards
- Tezcatara's Ember enchantment no longer softlocks Pandora's Box relic
- Added StS1 relics: Bag of Preparation, Regal Pillow, Pandora's Box, Nunchaku
Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

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