Alchemical Coffer
Ancient
Upon pickup, gain 4 potion slots filled with random potions.
Picking it up raises your potion slot count by 4 and immediately fills those four new slots with random potions rolled by the combat potion generator. It is a one-time pickup effect, so it cannot be traded away later, and the extra slots stay for the rest of the run. The potions are placed into the new slots specifically, so anything you were already carrying is untouched.
Rarity
Ancient
Character
All characters
When to take Alchemical Coffer
An Orobas offer, take it when your run is fragile and needs immediate resources, or you plan to lean on potions through act 2. Pass for an option that gives a lasting engine you lack.
Cards that synergize with Alchemical Coffer
Alchemize
Skill
1
Procure a random potion.
Exhaust.
Exhaust.
AlchemizeAlchemize refills slots mid-run.Procure a random potion.
Exhaust.
Exhaust.
Relics that synergize with Alchemical Coffer
White Beast StatueWhite Beast StatueWhite Beast Statue and Tiny Mailbox keep the extra slots full.Potions always appear in combat rewards.
Tiny MailboxTiny MailboxWhite Beast Statue and Tiny Mailbox keep the extra slots full.Whenever you Rest, procure 2 random potions.
Reptile TrinketReptile TrinketReptile Trinket turns every quaff into 3 Strength for the turn.Whenever you use a potion, gain 3 Strength this turn.
Entropic Brew refills every empty slot at once.
As offered in events
Gain 4 potion slots filled with random potions.
Related relics
Changes by version
- 12 Mar 2026Bug fixPotion BeltFixed softlock when any player has Potion Belt and Alchemical Coffer relics
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