Demise

Demise

Debuff
At the end of its turn, this creature X loses HP.

Only the Powdered Demise potion applies this, with 9 stacks. At the end of the target's turn, after its attacks, it takes damage equal to the stacks. The damage is unblockable and unpowered, so Block, Strength, Vulnerable and every other damage modifier are ignored. It never decays and never ticks down, so it repeats every enemy turn for the rest of the fight.

Kind
DemiseDebuff
Stacks
Yes
Applied by
1 potion

Where it comes from

Potions that apply Demise

Notes

A second potion on the same target adds 9 more per turn. The damage has no dealer, so nothing that reacts to being hit responds. It is a debuff, so Misery can spread it to every other enemy. Best on high-HP bosses; wasted on fights that end in two turns.

Changes by version

  1. 21 Aug 2025TextInternal playtest
    Updated wording

Internal playtest notes are from before the Early Access release. Names and numbers in them can differ from the game today.

Purchase today
If you haven't bought Slay The Spire 2 yet, it's time. Support the devs, they made an amazing game.Get it on Steam